Inverse Agonist Activity of Sarpogrelate, a Selective 5-HT2A-Receptor Antagonist, at the Constitutively Active Human 5-HT2A Receptor
Mutations producing constitutively active G-protein coupled receptors have been found in the pathophysiology of several diseases, implying that inverse agonists at the constitutively active receptors may have preferred therapeutic applications. Because of the involvement of 5-HT2A receptors in media...
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Main Authors: | , , , , |
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Format: | Book |
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Elsevier,
2006-01-01T00:00:00Z.
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Call Number: |
A1234.567 |
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Copy 1 | Available |