Targeting the T-type calcium channel Cav3.2 in GABAergic arcuate nucleus neurons to treat obesity

• Main Authors: Bing Feng (Author), Jerney Harms (Author), Nirali Patel (Author), Hui Ye (Author), Pei Luo (Author), Valeria Torres Irizarry (Author), Jacob Vidrine (Author), Ann Coulter (Author), Candida J. Rebello (Author), Sangho Yu (Author), Jia Fan (Author), Hans-Rudolf Berthoud (Author), Frank Greenway (Author), Heike Münzberg (Author), Christopher Morrison (Author), Pingwen Xu (Author), Yanlin He (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Cav3.2, a T-type low voltage-activated calcium channel widely expressed throughout the central nervous system, plays a vital role in neuronal excitability and various physiological functions. However, the effects of Cav3.2 on energy homeostasis remain unclear. Here, we examined the role o...