Pharmacological Profile of the Novel Anti-inflammatory Corticosteroid NS-126, a Therapeutic Agent for Allergic Rhinitis

• Main Authors: Naoki Inoue (Author), Asami Hashino (Author), Kiyoto Kageyama (Author), Xin Zhang (Author), Takahiro Sasagawa (Author), Naoko Kawakita (Author), Yosuke Takahashi (Author), Katsumi Yoshida (Author), Mikiko Hashimoto (Author), Kazuya Mori (Author), Takashi Kyoi (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

NS-126 (9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-cyclohexanecarboxylate 17-cyclopropanecarboxylate) is a novel, highly lipophilic anti-inflammatory corticosteroid. We compared NS-126 and the widely used intranasal corticosteroid fluticasone propionate (FP) in a guinea-p...