Risk reduction for small cell cancer of the ovary, hypercalcemic type in prepubertal patient: A clinical and bioethical perspective

• Main Authors: John A. Vu (Author), Whitney S. Thompson (Author), Denise B. Klinkner (Author), Asma Chattha (Author), Myra Wick (Author), Ellen J. Case (Author), Christopher Collura (Author), Amanika Kumar (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Loss of heterozygosity in the SMARCA4 gene is a hallmark feature of small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), an aggressive ovarian cancer occurring in young adults and adolescents with an average age of 23 years and a median survival of less than fifteen months following diagn...