CD22 blockade modulates microglia activity to suppress neuroinflammation following intracerebral hemorrhage

• Main Authors: Honglei Ren (Author), Yan Pan (Author), Danni Wang (Author), Hongying Hao (Author), Ranran Han (Author), Caiyun Qi (Author), Wenjun Zhang (Author), Wenyan He (Author), Fu-Dong Shi (Author), Qiang Liu (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Microglia are first responders to acute brain insults and initiate neuroinflammation to drive secondary tissue injury. Yet the key molecular switches in control of the inflammatory activity of microglia remain poorly understood. Intracerebral hemorrhage (ICH) is a devastating stroke subtype whereby...