Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase

• Main Authors: Saul S. Siller (Author), Kendal Broadie (Author)
• פורמט: ספר
• יצא לאור: The Company of Biologists, 2011-09-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

SUMMARY Fragile X syndrome (FXS), caused by loss of the fragile X mental retardation 1 (FMR1) product (FMRP), is the most common cause of inherited intellectual disability and autism spectrum disorders. FXS patients suffer multiple behavioral symptoms, including hyperactivity, disrupted circadian cy...