Oral colon-targeting core-shell microparticles loading curcumin for enhanced ulcerative colitis alleviating efficacy

• Main Authors: Chen Zhang (Author), Zhejie Chen (Author), Yanan He (Author), Jing Xian (Author), Ruifeng Luo (Author), Chuan Zheng (Author), Jinming Zhang (Author)
• Format: Book
• Published: BMC, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The oral colon-targeting drug delivery vehicle is vital for the efficient application of curcumin (Cur) in ulcerative colitis (UC) treatment because of its lipophilicity and instability in the gastrointestinal tract. Methods The core-shell microparticle (MP) system composed of ec...