Exosomal Dvl3 promoted the aggressive phenotypic transformation of RA-FLS via wnt pathway

• Main Authors: Weixing Tan (Author), Ning Chen (Author), Yang Qiu (Author), Xiaomei Feng (Author), Shuwen Li (Author), Yongjin Zhang (Author), Haoran Li (Author), Jie Gao (Author), Dongbao Zhao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective This study was performed to explore the function and mechanism of Dvl3 in RA-FLS by exosome intervention. Methods The expression pattern of Dvl3 was examined by IHC, WB, and qPCR. Modified exosomes obtained from culturing supernatant of RA-FLS infected with Dvl3 over expression (OE) lentiv...