Therapeutic Hypothermia Improves Hind Limb Motor Outcome and Attenuates Oxidative Stress and Neuronal Damage in the Lumbar Spinal Cord Following Cardiac Arrest

• Main Authors: Ji Hyeon Ahn (Author), Tae-Kyeong Lee (Author), Bora Kim (Author), Jae-Chul Lee (Author), Hyun-Jin Tae (Author), Jeong Hwi Cho (Author), Yoonsoo Park (Author), Myoung Cheol Shin (Author), Taek Geun Ohk (Author), Chan Woo Park (Author), Jun Hwi Cho (Author), Seongkweon Hong (Author), Joon Ha Park (Author), Soo Young Choi (Author), Moo-Ho Won (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypothermia enhances outcomes of patients after resuscitation after cardiac arrest (CA). However, the underlying mechanism is not fully understood. In this study, we investigated effects of hypothermic therapy on neuronal damage/death, microglial activation, and changes of endogenous antioxidants in...