Glimepiride Treatment Upon Reperfusion Limits Infarct Size via the phosphatidylinositol 3-Kinase/Akt Pathway in Rabbit Hearts

The phenomenon termed postconditioning, that is, brief episodes of ischemia/reperfusion at the onset of reperfusion reduce infarct size, is thought to involve the activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. Treatment with a drug activating PI3K at the onset of reperfusion may...

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Main Authors: Hirofumi Nishida (Author), Toshiaki Sato (Author), Momoko Nomura (Author), Masaru Miyazaki (Author), Haruaki Nakaya (Author)
Format: Book
Published: Elsevier, 2009-01-01T00:00:00Z.
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