Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS

• Autori principali: Xunxun Wu (Autore), Lian Liu (Autore), Qiuling Zheng (Autore), Hui Ye (Autore), Hua Yang (Autore), Haiping Hao (Autore), Ping Li (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2023-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Ischemic preconditioning (IPC) is a potential intervention known to protect the heart against ischemia/reperfusion injury, but its role in the no-reflow phenomenon that follows reperfusion is unclear. Dihydrotanshinone I (DT) is a natural compound and this study illustrates its role in cardiac ische...