Tetrahydrobiopterin: Beyond Its Traditional Role as a Cofactor

• Main Authors: Tuany Eichwald (Author), Lucila de Bortoli da Silva (Author), Ananda Christina Staats Pires (Author), Laís Niero (Author), Erick Schnorrenberger (Author), Clovis Colpani Filho (Author), Gisele Espíndola (Author), Wei-Lin Huang (Author), Gilles J. Guillemin (Author), José E. Abdenur (Author), Alexandra Latini (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tetrahydrobiopterin (BH4) is an endogenous cofactor for some enzymatic conversions of essential biomolecules, including nitric oxide, and monoamine neurotransmitters, and for the metabolism of phenylalanine and lipid esters. Over the last decade, BH4 metabolism has emerged as a promising metabolic t...