Interleukin-33 Induces Neutrophil Extracellular Trap (NET) Formation and Macrophage Necroptosis via Enhancing Oxidative Stress and Secretion of Proatherogenic Factors in Advanced Atherosclerosis

• Main Authors: Manoj Kumar Tembhre (Author), Mukesh Kumar Sriwastva (Author), Milind Padmakar Hote (Author), Shikha Srivastava (Author), Priyanka Solanki (Author), Shafaque Imran (Author), Ramakrishnan Lakshmy (Author), Alpana Sharma (Author), Kailash Jaiswal (Author), Ashish Datt Upadhyay (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin-33 (IL-33) acts as an 'alarmin', and its role has been demonstrated in driving immune regulation and inflammation in many human diseases. However, the precise mechanism of action of IL-33 in regulating neutrophil and macrophage functioning is not defined in advanced atheroscler...