Accumulation of mitochondrial DNA with a point mutation in tRNALeu(UUR) gene induces brain dysfunction in mice

• Main Authors: Kaori Ishikawa (Author), Daiki Miyata (Author), Satoko Hattori (Author), Haruna Tani (Author), Takayoshi Kuriyama (Author), Fan-Yan Wei (Author), Tsuyoshi Miyakawa (Author), Kazuto Nakada (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brain functions are mediated via the complex interplay between several complex factors, and hence, identifying the underlying cause of an abnormality within a certain brain region can be challenging. In mitochondrial disease, abnormalities in brain function are thought to be attributed to accumulati...