A Novel Anti-Kv10.1 Nanobody Fused to Single-Chain TRAIL Enhances Apoptosis Induction in Cancer Cells

• Main Authors: Franziska Hartung (Author), Thomas Krüwel (Author), Xiaoyi Shi (Author), Klaus Pfizenmaier (Author), Roland Kontermann (Author), Patrick Chames (Author), Frauke Alves (Author), Luis A. Pardo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antibody-based therapies hold promise for a safe and efficient treatment of cancer. The identification of target tumor cells through a specific antigen enriched on their surface and the subsequent delivery of the therapeutic agent only to those cells requires, besides the efficacy of the therapeutic...