B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma

Abstract Background Primary central nervous system lymphoma (PCNSL) is an uncommon tumor in the brain. Although most PCNSL are readily diagnosed as diffuse large B cell lymphoma (DLBCL) on the first biopsy, very rare cases have been described in which the first detected intracerebral lesions are non...

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Bibliographic Details
Main Authors: Rodrigo Javier (Author), Nawal Shaikh (Author), Maciej S. Lesniak (Author), Adam Sonabend (Author), Roger Stupp (Author), Amir Behdad (Author), Craig Horbinski (Author)
Format: Book
Published: BMC, 2018-06-01T00:00:00Z.
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Summary:Abstract Background Primary central nervous system lymphoma (PCNSL) is an uncommon tumor in the brain. Although most PCNSL are readily diagnosed as diffuse large B cell lymphoma (DLBCL) on the first biopsy, very rare cases have been described in which the first detected intracerebral lesions are non-neoplastic, and are composed mostly of perivascular T cells, not B cells. This phenomenon is known as "sentinel lesions."
Item Description:10.1186/s13000-018-0717-9
1746-1596