17β-Estradiol Abrogates Oxidative Stress and Neuroinflammation after Cortical Stab Wound Injury

• Main Authors: Kamran Saeed (Author), Myeung Hoon Jo (Author), Jun Sung Park (Author), Sayed Ibrar Alam (Author), Ibrahim Khan (Author), Riaz Ahmad (Author), Amjad Khan (Author), Rahat Ullah (Author), Myeong Ok Kim (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Disruptions in brain energy metabolism, oxidative damage, and neuroinflammation are commonly seen in traumatic brain injury (TBI). Microglial activation is the hallmark of neuroinflammation. After brain injury, microglia also act as a double-edged sword with distinctive phenotypic changes. Therefore...