Klf6 protects β-cells against insulin resistance-induced dedifferentiation
Objectives: In the pathogenesis of type 2 diabetes, development of insulin resistance triggers an increase in pancreatic β-cell insulin secretion capacity and β-cell number. Failure of this compensatory mechanism is caused by a dedifferentiation of β-cells, which leads to insufficient insulin secret...
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Main Authors: | , , , , , , , |
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Format: | Book |
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Elsevier,
2020-05-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |