Effective Osteogenic Priming of Mesenchymal Stem Cells through LNA-ASOs-Mediated <i>Sfrp1</i> Gene Silencing

• Main Authors: Daniel García-Sánchez (Author), Alberto González-González (Author), Patricia García-García (Author), Ricardo Reyes (Author), María Isabel Pérez-Núñez (Author), José A. Riancho (Author), Carmen Évora (Author), José Carlos Rodríguez-Rey (Author), Flor M. Pérez-Campo (Author)
• 格式: 图书
• 出版: MDPI AG, 2021-08-01T00:00:00Z.
• 主题: article
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Mesenchymal stem cell (MSC) transplantation has emerged as a promising approach for bone regeneration. Importantly, the beneficial effects of MSCs can be improved by modulating the expression levels of specific genes to stimulate MSC osteogenic differentiation. We have previously shown that <i>...