Exploring the contribution of estrogen to amyloid-beta regulation:a novel multifactorial computational modeling approach

• Kaituhi matua: Thomas J. Anastasio (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2013-03-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

According to the amyloid hypothesis, Alzheimer Disease results from the accumulation beyond normative levels of the peptide amyloid-β (Aβ). Perhaps because of its pathological potential, Aβ and the enzymes that produce it are heavily regulated by the molecular interactions occurring within cells, in...