Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes

• Main Authors: Tora I. Henriksen (Author), Peter K. Davidsen (Author), Maria Pedersen (Author), Heidi S. Schultz (Author), Ninna S. Hansen (Author), Therese J. Larsen (Author), Allan Vaag (Author), Bente K. Pedersen (Author), Søren Nielsen (Author), Camilla Scheele (Author)
• Format: Book
• Published: Elsevier, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: MicroRNAs (miRNAs) are increasingly recognized as fine-tuning regulators of metabolism, and are dysregulated in several disease conditions. With their capacity to rapidly change gene expression, miRNAs are also important regulators of development and cell differentiation. In the current s...