RAGE receptor and its soluble isoforms in diabetes mellitus complications

• Main Authors: Mauren Isfer Anghebem Oliveira (Author), Emanuel Maltempi de Souza (Author), Fábio de Oliveira Pedrosa (Author), Rosângela Roginski Réa (Author), Alexessander da Silva Couto Alves (Author), Geraldo Picheth (Author), Fabiane Gomes de Moraes Rego (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2013-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic hyperglycemia, which is present in all types of diabetes, increases the formation of advanced glycation end-products (AGEs). The interaction of AGEs with receptor of advanced glycation end-products (RAGE) initiates a cascade of pro-inflammatory and pro-coagulant processes that result in oxid...