Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation
Objective: Obesity and high fat diet (HFD) consumption in rodents is associated with hypothalamic inflammation and reactive gliosis. While neuronal inflammation promotes HFD-induced metabolic dysfunction, the role of astrocyte activation in susceptibility to hypothalamic inflammation and diet-induce...
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Elsevier,
2017-04-01T00:00:00Z.
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