The role of SIRT1-FXR signaling pathway in valproic acid induced liver injury: a quantitative targeted metabolomic evaluation in epileptic children
AimThis study aimed to gain deeper insights into the hepatotoxicity mechanisms of valproic acid (VPA), as well as to identify potential risk markers for VPA-induced hepatotoxicity.MethodsTwenty-two children with epilepsy treated with VPA monotherapy were divided into a normal liver function (NLF) gr...
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Frontiers Media S.A.,
2024-11-01T00:00:00Z.
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