TLR4/AP-1-Targeted Anti-Inflammatory Intervention Attenuates Insulin Sensitivity and Liver Steatosis

• Main Authors: Xiang Hu (Author), Jing Zhou (Author), Sha-sha Song (Author), Wen Kong (Author), Yan-Chuan Shi (Author), Lu-Lu Chen (Author), Tian-Shu Zeng (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Insulin resistance has been shown to be the common pathogenesis of many metabolic diseases. Metainflammation is one of the important characteristics of insulin resistance. Macrophage polarization mediates the production and development of metainflammation. Toll-like receptor 4 (TLR4) mediates macrop...