New arylsparteine derivatives as positive inotropic drugs

• Main Authors: Vito Boido (Author), Marcella Ercoli (Author), Michele Tonelli (Author), Federica Novelli (Author), Bruno Tasso (Author), Fabio Sparatore (Author), Elena Cichero (Author), Paola Fossa (Author), Paola Dorigo (Author), Guglielmina Froldi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Positive inotropic agents are fundamental in the treatment of heart failure; however, their arrhythmogenic liability and the increased myocardial oxygen demand strongly limit their therapeutic utility. Pursuing our study on cardiovascular activities of lupin alkaloid derivatives, several 2-(4-substi...