Progranulin in Musculoskeletal Inflammatory and Degenerative Disorders, Focus on Rheumatoid Arthritis, Lupus and Intervertebral Disc Disease: A Systematic Review

• Main Authors: María González-Rodríguez (Author), Djedjiga Ait Edjoudi (Author), Alfonso Cordero Barreal (Author), Clara Ruiz-Fernández (Author), Mariam Farrag (Author), Beatriz González-Rodríguez (Author), Francisca Lago (Author), Maurizio Capuozzo (Author), Miguel Angel Gonzalez-Gay (Author), Antonio Mera Varela (Author), Jesús Pino (Author), Yousof Farrag (Author), Oreste Gualillo (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Progranulin (PGRN) is a glycoprotein formed by 593 amino acids encoded by the GRN gene. It has an important role in immunity and inflammatory response, as well as in tissue recovery. Its role in musculoskeletal inflammatory diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus (SL...