A phase I, first‐in‐human study investigating the safety, tolerability, and pharmacokinetics of the maturation inhibitor GSK3739937

• Главные авторы: Paul D. Benn (Автор), Ying Zhang (Автор), Lesley Kahl (Автор), Thomas J. Greene (Автор), Veronica Bainbridge (Автор), Cindy Fishman (Автор), Bo Wen (Автор), Martin Gartland (Автор)
• Формат: ‌
• Опубликовано: Wiley, 2023-06-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract We report the safety and pharmacokinetic properties of the HIV‐1 maturation inhibitor GSK3739937 (GSK'937) in healthy participants. This was a phase I, first‐in‐human, double‐blind, randomized, placebo‐controlled, single‐ (part 1) and multiple‐ (part 2) dose escalation study with an ad...