A phase I, first‐in‐human study investigating the safety, tolerability, and pharmacokinetics of the maturation inhibitor GSK3739937

• Main Authors: Paul D. Benn (Author), Ying Zhang (Author), Lesley Kahl (Author), Thomas J. Greene (Author), Veronica Bainbridge (Author), Cindy Fishman (Author), Bo Wen (Author), Martin Gartland (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We report the safety and pharmacokinetic properties of the HIV‐1 maturation inhibitor GSK3739937 (GSK'937) in healthy participants. This was a phase I, first‐in‐human, double‐blind, randomized, placebo‐controlled, single‐ (part 1) and multiple‐ (part 2) dose escalation study with an ad...