Free Fatty Acid Receptor 1 Signaling Contributes to Migration, MMP-9 Activity, and Expression of IL-8 Induced by Linoleic Acid in HaCaT Cells

• Main Authors: Carolina Manosalva (Author), Pablo Alarcón (Author), Karina González (Author), Jorge Soto (Author), Karin Igor (Author), Fernanda Peña (Author), Gustavo Medina (Author), Rafael A. Burgos (Author), María A. Hidalgo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Keratinocytes and neutrophils are the main cellular components in wound healing during re-epithelization and inflammation. Free fatty acids such as linoleic acid (LA) present beneficial properties for wound healing by modulating the inflammatory response. LA is a natural ligand of free fatty acids r...