Depot specific differences in the adipogenic potential of precursors are mediated by collagenous extracellular matrix and Flotillin 2 dependent signaling

• Main Authors: Gerald Grandl (Author), Sebastian Müller (Author), Hansjörg Moest (Author), Caroline Moser (Author), Bernd Wollscheid (Author), Christian Wolfrum (Author)
• Format: Book
• Published: Elsevier, 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Adipose tissue shows a high degree of plasticity, and adipocyte hyperplasia is an important mechanism for adipose tissue expansion. Different adipose depots respond differently to an increased demand for lipid storage. Orchestrating cellular expansion in vivo requires extracellular matrix...