The Encapsulation of Citicoline within Solid Lipid Nanoparticles Enhances Its Capability to Counteract the 6-Hydroxydopamine-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells

• Main Authors: Andrea Margari (Author), Anna Grazia Monteduro (Author), Silvia Rizzato (Author), Loredana Capobianco (Author), Alessio Crestini (Author), Roberto Rivabene (Author), Paola Piscopo (Author), Mara D'Onofrio (Author), Valeria Manzini (Author), Giuseppe Trapani (Author), Alessandra Quarta (Author), Giuseppe Maruccio (Author), Carmelo Ventra (Author), Luigi Lieto (Author), Adriana Trapani (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

(1) Backgrond: Considering the positive effects of citicoline (CIT) in the management of some neurodegenerative diseases, the aim of this work was to develop CIT-Loaded Solid Lipid Nanoparticles (CIT-SLNs) for enhancing the therapeutic use of CIT in parkinsonian syndrome; (2) Methods: CIT-SLNs were...