Simplified ⁸⁹Zr-Labeling Protocol of Oxine (8-Hydroxyquinoline) Enabling Prolonged Tracking of Liposome-Based Nanomedicines and Cells

• Main Authors: Andras Polyak (Author), Jens P. Bankstahl (Author), Karen F. W. Besecke (Author), Constantin Hozsa (Author), Wiebke Triebert (Author), Rajeswara Rao Pannem (Author), Felix Manstein (Author), Thomas Borcholte (Author), Marcus Furch (Author), Robert Zweigerdt (Author), Robert K. Gieseler (Author), Frank M. Bengel (Author), Tobias L. Ross (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this work, a method for the preparation of the highly lipophilic labeling synthon [⁸⁹Zr]Zr(oxinate)₄ was optimized for the radiolabeling of liposomes and human induced pluripotent stem cells (hiPSCs). The aim was to establish a robust and reliable lab...