Simvastatin ameliorates oxidative stress levels in HepG2 cells and hyperlipidemic rats

• Main Authors: Kanika Verma (Author), Shikha Makwana (Author), Sarvesh Paliwal (Author), Vartika Paliwal (Author), Smita Jain (Author), Swati Paliwal (Author), Swapnil Sharma (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Simvastatin is an established anti-hyperlipidemic drug and few studies have indicated its role in the mitigation of oxidative stress. However, a systematic study considering molecular binding/interaction of simvastatin with anti-oxidant enzymes followed by confirmational in vitro and in vivo studies...