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Prediction of Drug-Drug Interaction Potential of Tegoprazan Using Physiologically Based Pharmacokinetic Modeling and Simulation

This study aimed to develop a physiologically based pharmacokinetic (PBPK) model of tegoprazan and to predict the drug-drug interaction (DDI) potential between tegoprazan and cytochrome P450 (CYP) 3A4 perpetrators. The PBPK model of tegoprazan was developed using SimCYP Simulator<sup>®</sup...

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Main Authors:	Deok Yong Yoon (Author), SeungHwan Lee (Author), In-Jin Jang (Author), Myeongjoong Kim (Author), Heechan Lee (Author), Seokuee Kim (Author), Bongtae Kim (Author), Geun Seog Song (Author), Su-jin Rhee (Author)
Format:	Book
Published:	MDPI AG, 2021-09-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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