Improving NonViral Gene Delivery Using MHz Bursts of Nanosecond Pulses and Gold Nanoparticles for Electric Field Amplification

• Main Authors: Eivina Radzevičiūtė-Valčiukė (Author), Jovita Gečaitė (Author), Augustinas Želvys (Author), Auksė Zinkevičienė (Author), Rokas Žalnėravičius (Author), Veronika Malyško-Ptašinskė (Author), Aušra Nemeikaitė-Čenienė (Author), Vytautas Kašėta (Author), Natalija German (Author), Jurij Novickij (Author), Almira Ramanavičienė (Author), Julita Kulbacka (Author), Vitalij Novickij (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gene delivery by the pulsed electric field is a promising alternative technology for nonviral transfection; however, the application of short pulses (i.e., nanosecond) is extremely limited. In this work, we aimed to show the capability to improve gene delivery using MHz frequency bursts of nanosecon...