High Glucose Level Disturbs the Resveratrol-Evoked Curtailment of CX3CL1/CX3CR1 Signaling in Human Placental Circulation

• Main Authors: Dariusz Szukiewicz (Author), Michal Pyzlak (Author), Grzegorz Szewczyk (Author), Aleksandra Stangret (Author), Seweryn Trojanowski (Author), Michal Bachanek (Author), Wojciech Braksator (Author), Jaroslaw Wejman (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hyperglycemia-induced hyperactivity of chemokine CX3CL1 (fractalkine) occurs in the human placenta. Anti-inflammatory/antioxidant activities of resveratrol (3,5,4'-trihydroxy-trans-stilbene) are related to the modulation of chemokine CX3CL1 and its receptor, CX3CR1, signaling pathways. We exami...