Synthesis, Evaluation of Vasorelaxant Activity, and Molecular Docking of Pyranopyrazole Derivatives as Calcium Channel Blockers

• Prif Awduron: Saghar Mowlazadeh Haghighi (Awdur), Mohammad Fathalipour (Awdur), Maryam Abbasi (Awdur), Azar Purkhosrow (Awdur), Somayeh Oftadehgan (Awdur), Ali Khalafi-Nezhad (Awdur), Elahe Sattarinezhad (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Shiraz University of Medical Sciences, 2023-06-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Pyranopyrazole analogs are novel synthetic compounds with many biological activities. In this research,we synthesized six new pyranopyrazole derivatives using a biocompatible catalyst and evaluated their vasorelaxant and calcium channel binding properties in isolated rat thoracic aorta. Male Sprague...