Anticancer Activity of Half-Sandwich Ru, Rh and Ir Complexes with Chrysin Derived Ligands: Strong Effect of the Side Chain in the Ligand and Influence of the Metal

• Main Authors: Ana R. Rubio (Author), Rocío González (Author), Natalia Busto (Author), Mónica Vaquero (Author), Ana L. Iglesias (Author), Félix A. Jalón (Author), Gustavo Espino (Author), Ana M. Rodríguez (Author), Begoña García (Author), Blanca R. Manzano (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An important challenge in the field of anticancer chemotherapy is the search for new species to overcome the resistance of standard drugs. An interesting approach is to link bioactive ligands to metal fragments. In this work, we have synthesized a set of <i>p</i>-cymene-Ru or cyclopentad...