Targeting Autophagy for Developing New Therapeutic Strategy in Intervertebral Disc Degeneration

• Main Authors: Md Entaz Bahar (Author), Jin Seok Hwang (Author), Mahmoud Ahmed (Author), Trang Huyen Lai (Author), Trang Minh Pham (Author), Omar Elashkar (Author), Kazi-Marjahan Akter (Author), Dong-Hee Kim (Author), Jinsung Yang (Author), Deok Ryong Kim (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intervertebral disc degeneration (IVDD) is a prevalent cause of low back pain. IVDD is characterized by abnormal expression of extracellular matrix components such as collagen and aggrecan. In addition, it results in dysfunctional growth, senescence, and death of intervertebral cells. The biological...