FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines

• Main Authors: Ke Su (Author), Ping Zeng (Author), Wei Liang (Author), Zhengyu Luo (Author), Yiman Wang (Author), Xifeng Lv (Author), Qi Han (Author), Miao Yan (Author), Cheng Chen (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

FTY720, a new chemical substance derived from the ascomycete Isaria sinclairii, is used for treating multiple sclerosis, renal cancer, and asthma. Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid metabolite and exists in red blood cells. FTY720 is a synthetic S1P analog which can block S1P...