Renal ROCK Activation and Its Pharmacological Inhibition in Patients With Diabetes

• 主要な著者: Keiichiro Matoba (著者), Kensuke Sekiguchi (著者), Yosuke Nagai (著者), Yusuke Takeda (著者), Hiroshi Takahashi (著者), Tamotsu Yokota (著者), Kazunori Utsunomiya (著者), Rimei Nishimura (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Rho-associated coiled-coil-containing protein kinase (ROCK) is a serine/threonine kinase with essential roles in cytoskeletal functions. Substantial evidence implicates ROCK as a critical regulator in the inception and progression of diabetic nephropathy through a mechanism involving mesangial fibro...