Pharmacokinetics and Metabolism of Naringin and Active Metabolite Naringenin in Rats, Dogs, Humans, and the Differences Between Species

• Main Authors: Yang Bai (Author), Wei Peng (Author), Cuiping Yang (Author), Wei Zou (Author), Menghua Liu (Author), Hao Wu (Author), Loudi Fan (Author), Peibo Li (Author), Xuan Zeng (Author), Weiwei Su (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundPharmacokinetics provides a scientific basis for drug product design, dosage regimen planning, understanding the body's action on the drug, and relating the time course of the drug in the body to its pharmacodynamics and/or toxic effects. Recently, naringin, a natural flavonoid, was a...