Ex Vivo Visualization of Distribution of Intravitreal Injections in the Porcine Vitreous and Hydrogels Simulating the Vitreous

• Main Authors: Tobias Auel (Author), Lara Paula Scherke (Author), Stefan Hadlich (Author), Susan Mouchantat (Author), Michael Grimm (Author), Werner Weitschies (Author), Anne Seidlitz (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The characterization of intravitreal dosage forms with regard to their behavior in vivo is usually explored in preclinical development through animal studies. In vitro vitreous substitutes (VS) to simulate the vitreous body for preclinical investigations have so far been insufficiently studied. To d...