A rapid and sensitive liquid chromatography-tandem mass spectrometric method for the determination of hederasaponin B in rat plasma: Application to a pharmacokinetic study

• Main Authors: Jiaxin Liu (Author), Xueyan Yang (Author), Lin Li (Author), Qili Zhang (Author), Zhaoyan Zhang (Author), Xin Zhang (Author), Yunli Zhao (Author), Miao Yu (Author), Zhiguo Yu (Author)
• Format: Book
• Published: Elsevier, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A rapid, simple and sensitive ultra-high performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) method was developed and validated for the determination of hederasaponin B, an active triterpenoid saponin widely existed in Hedera helix L. Plasma samples were processed by protein pre...