Process-Induced Crystal Surface Anisotropy and the Impact on the Powder Properties of Odanacatib

• Váldodahkkit: Isha Bade (Dahkki), Vikram Karde (Dahkki), Luke Schenck (Dahkki), Marina Solomos (Dahkki), Margaret Figus (Dahkki), Chienhung Chen (Dahkki), Stephanus Axnanda (Dahkki), Jerry Y. Y. Heng (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2024-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Crystalline active pharmaceutical ingredients with comparable size and surface area can demonstrate surface anisotropy induced during crystallization or downstream unit operations such as milling. To the extent that varying surface properties impacts bulk powder properties, the final drug product pe...