A Novel Class of Potent Anti-Tyrosinase Compounds with Antioxidant Activity, 2-(Substituted phenyl)-5-(trifluoromethyl)benzo[<i>d</i>]thiazoles: In Vitro and In Silico Insights

• Main Authors: YeJi Hwang (Author), Jieun Lee (Author), Hee Jin Jung (Author), Sultan Ullah (Author), Jeongin Ko (Author), Yeongmu Jeong (Author), Yu Jung Park (Author), Min Kyung Kang (Author), Hwayoung Yun (Author), Min-Soo Kim (Author), Pusoon Chun (Author), Hae Young Chung (Author), Hyung Ryong Moon (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sixteen compounds bearing a benzothiazole moiety were synthesized as potential tyrosinase inhibitors and evaluated for mushroom tyrosinase inhibitory activity. The compound 4-(5-(trifluoromethyl)benzo[<i>d</i>]thiazol-2-yl)benzene-1,3-diol (compound <b>1b</b>) exhibited the h...