Berberine Protects Against NLRP3 Inflammasome via Ameliorating Autophagic Impairment in MPTP-Induced Parkinson's Disease Model

• Main Authors: Shuxuan Huang (Author), Hanqun Liu (Author), Yuwan Lin (Author), Muchang Liu (Author), Yanhua Li (Author), Hengxu Mao (Author), Zhiling Zhang (Author), Yunlong Zhang (Author), Panghai Ye (Author), Liuyan Ding (Author), Ziting Zhu (Author), Xinling Yang (Author), Chaojun Chen (Author), Xiaoqin Zhu (Author), Xiaoyun Huang (Author), Wenyuan Guo (Author), Pingyi Xu (Author), Lin Lu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The NLR family pyrin domain containing 3 (NLRP3) inflammasome was reported to be regulated by autophagy and activated during inflammatory procession of Parkinson's disease (PD). Berberine (BBR) is well-studied to play an important role in promoting anti-inflammatory response to mediate the auto...