Ebola virion attachment and entry into human macrophages profoundly effects early cellular gene expression.

• Автори: Victoria Wahl-Jensen (Автор), Sabine Kurz (Автор), Friedericke Feldmann (Автор), Lukas K Buehler (Автор), Jason Kindrachuk (Автор), Victor DeFilippis (Автор), Jean da Silva Correia (Автор), Klaus Früh (Автор), Jens H Kuhn (Автор), Dennis R Burton (Автор), Heinz Feldmann (Автор)
• Формат: Книга
• Опубліковано: Public Library of Science (PLoS), 2011-10-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Zaire ebolavirus (ZEBOV) infections are associated with high lethality in primates. ZEBOV primarily targets mononuclear phagocytes, which are activated upon infection and secrete mediators believed to trigger initial stages of pathogenesis. The characterization of the responses of target cells to ZE...