Recent Research Advances in Small-Molecule Pan-PIM Inhibitors

• Główni autorzy: Lei Xu (Autor), Yu-Cheng Meng (Autor), Peng Guo (Autor), Ming Li (Autor), Lei Shao (Autor), Jun-Hai Huang (Autor)
• Format: Książka
• Wydane: Georg Thieme Verlag KG, 2022-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract PIM kinase is consequently emerging as a promising target for cancer therapeutics and immunomodulation. PIM kinases are overexpressed in a variety of hematological malignancies and solid tumors, and their inhibition has become a strong therapeutic interest. Currently, some pan-PIM kinase in...