Induction of CYP3A activity by dexamethasone may not be strong, even at high doses: insights from a case of tacrolimus co-administration

Abstract Background Dexamethasone (DEX) induces CYP3A activity in a concentration-dependent manner. However, no study has examined changes in the blood concentration of CYP3A substrate drugs when DEX is administered at high doses. Herein, we present a case in which tacrolimus (TAC), a typical CYP3A...

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Main Authors: Yoshiyuki Ohno (Author), Toyohito Oriyama (Author), Akira Honda (Author), Mineo Kurokawa (Author), Tappei Takada (Author)
Format: Book
Published: BMC, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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